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Fts
Transgenic Allele Detail
Summary
Symbol: Fts
Name: fused toes
MGI ID: MGI:1860759
Synonyms: Ft
Gene: Fts  Location: Chr8:91632145-93455280 bp  Genetic Position: Chr8, cytoband D
Alliance: Fts page
Transgene
origin
Strain of Origin:  (C57BL/6 x SJL)F2
Transgene
description
Transgene Type:    Transgenic
Mutation:    Intergenic deletion
 
Mutation detailsThe Ft mutation is the result of a transgene integration into mouse chromosome 8. The transgene integration event resulted in a deletion of 1.6 Mb of genomic sequences, covering coding regions for six genes. Among these are the genes included in the entire IroquoisB (IrxB) gene cluster. (J:44450, J:76079)
Inheritance:    Semidominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 assay results
In Structures Affected by this Mutation: 11 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fts Mutation:  0 strains or lines available
References
Original:  J:20159 van der Hoeven F, et al., Programmed cell death is affected in the novel mouse mutant Fused toes (Ft). Development. 1994 Sep;120(9):2601-7
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory