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Targeted Allele Detail
Symbol: Ctu2tm1(KOMP)Wtsi
Name: cytosolic thiouridylase subunit 2; targeted mutation 1, Wellcome Trust Sanger Institute
MGI ID: MGI:4419518
Gene: Ctu2  Location: Chr8:123202882-123209831 bp, + strand  Genetic Position: Chr8, 71.26 cM
Alliance: Ctu2tm1(KOMP)Wtsi page
IMPC: Ctu2 gene page
Mutant Cell Lines:  EPD0410_4_B09, EPD0410_4_B10, EPD0410_4_C11, EPD0410_4_D10, EPD0410_4_D11, EPD0410_4_E09, EPD0410_4_E12, EPD0410_4_F10, EPD0410_4_F12, EPD0410_4_G11, EPD0410_4_G12
Germline Transmission:  Earliest citation of germline transmission: J:204812
Parent Cell Line:  JM8A3.N1 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: KOMP-CSD
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: L1L2_Bact_P
Mutation detailsThe insertion of the L1L2_Bact_P cassette created a deletion of size 2927 starting at position 123203249 and ending at position 123206176 of Chromosome 8 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. (J:148605, J:173534)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Ctu2 Mutation:  16 strains or lines available
Original:  J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009;
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory