Csf1^op
Spontaneous Allele Detail

Summary

• Symbol: Csf1^op
• Name: colony stimulating factor 1 (macrophage); osteopetrosis
• MGI ID: MGI:1856333
• Synonyms: Csf-1^op, Csf1^- op, csfmop, Csfm^op, M-, op
• Gene: Csf1 Location: Chr3:107648364-107667785 bp, - strand
• Alliance: Csf1^op page

Csf1^op/Csf1^op

Show the 3 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: B6;DW-Pou1f1^dw

Mutation description

• Allele Type: Spontaneous
• Mutation: Insertion
• Mutation details: A single nucleotide (T) insertion 262 bp downstream from the initiation codon resulted in a frameshift and the creation of a stop codon 21 bp downstream of the insertion. (J:10519)
• Inheritance: Recessive

Disease models

Expression

In Mice Carrying this Mutation:	5 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	33 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Csf1^op

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Csf1 Mutation: 45 strains or lines available

References

• Original: J:35678 Lane PW, Osteopetrosis (op). Mouse News Lett. 1973;48:35
• All: 236 reference(s)