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Tg(Lck-cre)1Cwi
Transgene Detail
Summary
Symbol: Tg(Lck-cre)1Cwi
Name: transgene insertion 1, Christopher B Wilson
MGI ID: MGI:2448686
Synonyms: cwLckCre, iLckcre, lck-cre, lckCre, Lck-Cre, Lck-Cre+, plck-cre, pLck-cre
Transgene: Tg(Lck-cre)1Cwi  Location: unknown  
Alliance: Tg(Lck-cre)1Cwi page
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F2
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Lck-cre)1Cwi expression driven by 1 gene
 
Mutation detailsThis transgene expresses Cre recombinase under the control of the Lck promoter, active in T cells during development. (J:73127)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Lck (species not specified)
Summary of all recombinase alleles driven by Lck.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 2 RNA-Seq or microarray experiment(s)
Tumor Data
List all tumor models in MMHCdb carrying Tg(Lck-cre)1Cwi
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
References
Original:  J:73127 Lee PP, et al., A critical role for dnmt1 and DNA methylation in T cell development, function, and survival. Immunity. 2001 Nov;15(5):763-74
All:  196 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
07/02/2024
MGI 6.13
The Jackson Laboratory