Cd79b^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Cd79b^m1Btlr
• Name: CD79B antigen; mutation 1, Bruce Beutler
• MGI ID: MGI:6268742
• Synonyms: hallasan
• Gene: Cd79b Location: Chr11:106202167-106205388 bp, - strand Genetic Position: Chr11, 68.89 cM
• Alliance: Cd79b^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Insertion
• Mutation details: ENU-induced G to T transversion at base pair 106,312,441 (v38) on chromosome 11, or base pair 2,122 in the GenBank genomic region NC_000077 within the splice acceptor site of intron 3. The effect of the mutation at the cDNA and protein levels has not been examined, but the mutation is predicted to result in the use of a cryptic splice site in exon 4. The resulting transcript would have a 7-base pair deletion of exon 4, which would cause a frame-shifted protein product beginning after amino acid 142 of the protein, which is normally 228 amino acids in length, and termination after the inclusion of five aberrant amino acids. (J:267537)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd79b Mutation: 36 strains or lines available

References

• Original: J:267537 Zhong X, et al., Mutagenetix entry for hallasan. MGI Direct Data Submission. 2018
• All: 1 reference(s)