Ace2^em2(ACE2)Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ace2^em2(ACE2)Gpt
• Name: angiotensin converting enzyme 2; endonuclease-mediated mutation 2, GemPharmatech Co., Ltd
• MGI ID: MGI:6452442
• Synonyms: Ace2^{em1Cin(hACE2-stop)}
• Gene: Ace2 Location: ChrX:162922338-162971414 bp, + strand Genetic Position: ChrX, 76.12 cM, cytoband F5
• Alliance: Ace2^em2(ACE2)Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Inserted expressed sequence)
• Mutation: Insertion
• Ace2^em2(ACE2)Gpt expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  ACE2 (59272)

  Ace2	(MGI:1917258)

• Mutation details: CRISPR/Cas9 technology inserted a chimeric coding sequence of the extracellular region of human ACE2 fused with the intracellular region and the transmembrane region of mouse Ace2 and stop codon into exon 1 of the gene (ENSMUST00000073973.10). (J:293217)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ace2 Mutation: 54 strains or lines available

References

• Original: J:293217 GemPharmatech, GemPharmatech Website. 2020
• All: 2 reference(s)