Tg(KRT14-cre/ERT2)1Ipc
Transgene Detail

Summary

• Symbol: Tg(KRT14-cre/ERT2)1Ipc
• Name: transgene insertion 1, I Pierre Chambon
• MGI ID: MGI:2177426
• Synonyms: K14-Cre:ER, K14-Cre-ER^T2
• Transgene: Tg(KRT14-cre/ERT2)1Ipc Location: unknown
• Alliance: Tg(KRT14-cre/ERT2)1Ipc page

Rxra^tm4Ipc/Rxra^tm4Ipc Rxrb^tm1Pcn/Rxrb^tm1Pcn Tg(KRT14-cre/ERT2)1Ipc/0 mice develop a chronic skin inflammation

Show the 4 phenotype image(s) involving this allele.

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F1

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(KRT14-cre/ERT2)1Ipc expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	KRT14

• Mutation details: This transgene expresses a tamoxifen-inducible form of cre recombinase in the epidermis, tongue, esophagus, stomach, and other epithelial tissues. (J:65109)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	KRT14 (species not specified) Summary of all recombinase alleles driven by KRT14. Comparative matrix view of recombinase activities

Tumor Data

List all tumor models in MMHCdb carrying Tg(KRT14-cre/ERT2)1Ipc

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:65109 Li M, et al., Skin abnormalities generated by temporally controlled RXRalpha mutations in mouse epidermis. Nature. 2000 Oct 5;407(6804):633-6
• All: 81 reference(s)