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Tnfrsf9m1Btlr
Chemically induced Allele Detail
Summary
Symbol: Tnfrsf9m1Btlr
Name: tumor necrosis factor receptor superfamily, member 9; mutation 1, Bruce Beutler
MGI ID: MGI:6200374
Synonyms: asilomar
Gene: Tnfrsf9  Location: Chr4:151004612-151030561 bp, + strand  Genetic Position: Chr4, 81.52 cM
Alliance: Tnfrsf9m1Btlr page
Mutation
origin
Strain of Origin:  C57BL/6J
Project Collection: Beutler Mutagenetix
Mutation
description
Allele Type:    Chemically induced (ENU) (Not Specified)
Mutation:    Single point mutation
 
Mutation detailsENU-induced T to C transition at base pair 150,929,874 (v38) on chromosome 4, or base pair 9,720 in the GenBank genomic region NC_000070 encoding Tnfrsf9. The mutation corresponds to residue 160 in the mRNA sequence NM_011612 within exon 1 of 8 total exons. The mutation results in a valine to alanine substitution at position 10 (V10A) in the CD137 protein. (J:265260)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tnfrsf9 Mutation:  46 strains or lines available
References
Original:  J:265260 Zhong X, et al., Mutagenetix entry for asilomar. MGI Direct Data Submission. 2018;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory