Del(7)Tyr^c-3H
Radiation induced Allele Detail

Summary

• Symbol: Del(7)Tyr^c-3H
• Name: deletion, Chr 7, albino 3 Harwell
• MGI ID: MGI:1856304
• Synonyms: c³, c^3H, D7Ssb3Hp, Tyr^c-3H
• Gene: Del(7)Tyr^c-3H Location: unknown Genetic Position: Chr7, Syntenic

Mutation origin

• Strain of Origin: (C3H/HeH x 101/H)F1

Mutation description

• Allele Type: Radiation induced
• Mutation: Intergenic deletion
• Large intergenic deletion that includes the Mod2 locus. (J:6053)
• Inheritance: Not Specified

Expression

In Mice Carrying this Mutation:	4 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(7)Tyr c-3H Mutation: 0 strains or lines available

Notes

This allele resembles two other induced mutant alleles, Tyr^c-65K and Tyr^c-112K, in most respects studied, including neonatal death, effect on liver enzymes and serum proteins (J:5435), and defective rough endoplasmic reticulum of liver (J:5386).

References

• Original: J:5063 Erickson RP, et al., Glucose-6-phosphatase deficiency caused by radiation-induced alleles at the albino locus in the mouse. Proc Natl Acad Sci U S A. 1968 Feb;59(2):437-44
• All: 18 reference(s)