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Notch2tm3Grid
Targeted Allele Detail
Summary
Symbol: Notch2tm3Grid
Name: notch 2; targeted mutation 3, Tom Gridley
MGI ID: MGI:3617328
Synonyms: N2f, N2flox, Notch2f, Notch2Fl, Notch2flox
Gene: Notch2  Location: Chr3:97920854-98057683 bp, + strand  Genetic Position: Chr3, 42.42 cM
Alliance: Notch2tm3Grid page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:105278
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    loxP sites were inserted to flank exon 3. (J:105278)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 106 assay results
1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 21 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Notch2 Mutation:  97 strains or lines available
References
Original:  J:105278 McCright B, et al., Generation of new Notch2 mutant alleles. Genesis. 2006 Jan;44(1):29-33
All:  85 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory