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Transgene Detail
Symbol: Tg(Tec-BCR/ABL1)5Hhi
Name: transgene insertion 5, Hisamaru Hirai
MGI ID: MGI:3039034
Transgene: Tg(Tec-BCR/ABL1)5Hhi  Location: unknown  
Alliance: Tg(Tec-BCR/ABL1)5Hhi page
Strain of Origin:  (C57BL/6 x DBA/2)F2
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
Tg(Tec-BCR/ABL1)5Hhi expresses 2 genes
Tg(Tec-BCR/ABL1)5Hhi expression driven by 1 gene
Mutation detailsFusion gene of human BCR and ABL1 encoding an oncogenic 210 kDa protein (p210BCR/ABL). Expression of the cDNA is controlled by the mouse Tec promoter. (J:46392)
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Tumor Data
List all tumor models in MMHCdb carrying Tg(Tec-BCR/ABL1)5Hhi
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Original:  J:46392 Honda H, et al., Development of acute lymphoblastic leukemia and myeloproliferative disorder in transgenic mice expressing p210bcr/abl: a novel transgenic model for human Ph1-positive leukemias. Blood. 1998 Mar 15;91(6):2067-75
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory