Ffar2^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Ffar2^tm1Dgen
• Name: free fatty acid receptor 2; targeted mutation 1, Deltagen
• MGI ID: MGI:4367910
• Synonyms: Gpr43^-
• Gene: Ffar2 Location: Chr7:30517778-30523200 bp, - strand Genetic Position: Chr7, 19.25 cM
• Alliance: Ffar2^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:153951
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• 55 bp of exon 3 were replaced with a neo and lacZ cassette. (J:153951)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Ffar2^tm1Dgen

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ffar2 Mutation: 25 strains or lines available

References

• Original: J:153951 Maslowski KM, et al., Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43. Nature. 2009 Oct 29;461(7268):1282-6
• All: 28 reference(s)