Slamf1^tm1Vei
Targeted Allele Detail

Summary

• Symbol: Slamf1^tm1Vei
• Name: signaling lymphocytic activation molecule family member 1; targeted mutation 1, Andre Veillette
• MGI ID: MGI:3512183
• Synonyms: slam^-
• Gene: Slamf1 Location: Chr1:171594700-171628752 bp, + strand Genetic Position: Chr1, 79.54 cM
• Alliance: Slamf1^tm1Vei page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:93886
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 was replaced with a neo cassette. Immunoblot and flow cytometry were unable to detect protein in mutants. (J:93886)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slamf1 Mutation: 24 strains or lines available

References

• Original: J:93886 Davidson D, et al., Genetic evidence linking SAP, the X-linked lymphoproliferative gene product, to Src-related kinase FynT in T(H)2 cytokine regulation. Immunity. 2004 Nov;21(5):707-17
• All: 4 reference(s)