Ilf3^tm1.1Itl
Targeted Allele Detail

Summary

• Symbol: Ilf3^tm1.1Itl
• Name: interleukin enhancer binding factor 3; targeted mutation 1.1, inGenious Targeting Laboratory
• MGI ID: MGI:4878917
• Synonyms: Ilf3^tm1.1Igl, NFAR^Flox
• Gene: Ilf3 Location: Chr9:21279167-21316657 bp, + strand Genetic Position: Chr9, 7.78 cM, cytoband A4-A5
• Alliance: Ilf3^tm1.1Itl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:167126
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2 and an FRT and loxP flanked neo cassette was inserted downstream of exon 5. Flp-mediated recombination removed the neo cassette leaving exons 2 through 5 floxed. (J:167126)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ilf3 Mutation: 78 strains or lines available

References

• Original: J:167126 Harashima A, et al., Phosphorylation of the NFAR proteins by the dsRNA-dependent protein kinase PKR constitutes a novel mechanism of translational regulation and cellular defense. Genes Dev. 2010 Dec 1;24(23):2640-53
• All: 1 reference(s)