Fcgr1^tm1Jgjw
Targeted Allele Detail

Summary

• Symbol: Fcgr1^tm1Jgjw
• Name: Fc receptor, IgG, high affinity I; targeted mutation 1, Jan G J van de Winkel
• MGI ID: MGI:3664782
• Synonyms: Gamma^-
• Gene: Fcgr1 Location: Chr3:96190225-96201285 bp, - strand Genetic Position: Chr3, 41.72 cM
• Alliance: Fcgr1^tm1Jgjw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:111170
• Parent Cell Line: BL/6-III (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neo replaced 1.5 kb of sequence including exon 2. RT-PCR confirmed absence of transcript. (J:111170)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fcgr1 Mutation: 34 strains or lines available

References

• Original: J:111170 van Vugt MJ, et al., FcR gamma-chain is essential for both surface expression and function of human Fc gamma RI (CD64) in vivo. Blood. 1996 May 1;87(9):3593-9
• All: 3 reference(s)