Cd79a^{tm1.1(BAP31N-EGFP)Pld}
Targeted Allele Detail

Summary

• Symbol: Cd79a^{tm1.1(BAP31N-EGFP)Pld}
• Name: CD79A antigen (immunoglobulin-associated alpha); targeted mutation 1.1, Roberta Pelanda
• MGI ID: MGI:2384631
• Synonyms: mEGFP/mb-1^inv
• Gene: Cd79a Location: Chr7:24596922-24601283 bp, + strand Genetic Position: Chr7, 13.49 cM
• Alliance: Cd79a^{tm1.1(BAP31N-EGFP)Pld} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:75114
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 through 5 were replaced by a fragment flanked by inverted loxP sites and containing sequence encoding a membrane-associated enhanced green fluorescent protein (GFP) followed downstream by a polyA signal and, in opposite orientation, the coding regions of exons 2 through 5. The absence of endogenous protein and the expression of GFP was confirmed by flow cytometric analysis of bone marrow, spleen, and lymph node cells. (J:75114)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd79a Mutation: 29 strains or lines available

References

• Original: J:75114 Pelanda R, et al., Cre recombinase-controlled expression of the mb-1 allele. Genesis. 2002 Feb;32(2):154-7
• All: 6 reference(s)