Zbtb7b^tm7Itan
Targeted Allele Detail

Summary

• Symbol: Zbtb7b^tm7Itan
• Name: zinc finger and BTB domain containing 7B; targeted mutation 7, Ichiro Taniuchi
• MGI ID: MGI:5506942
• Synonyms: Thpok^3S
• Gene: Zbtb7b Location: Chr3:89284953-89300976 bp, - strand Genetic Position: Chr3, 39.09 cM, cytoband A1-A2
• Alliance: Zbtb7b^tm7Itan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:195348
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Modified regulatory region)
• Mutation: Insertion
• Mutation details: The endogenous 5' silencer region was replaced with three copies of that same sequence and a neomycin resistance gene. (J:195348)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zbtb7b Mutation: 24 strains or lines available

References

• Original: J:195348 Tanaka H, et al., Epigenetic Thpok silencing limits the time window to choose CD4(+) helper-lineage fate in the thymus. EMBO J. 2013 Apr 17;32(8):1183-94
• All: 1 reference(s)