Nfil3^tm1.1Kubo
Targeted Allele Detail

Summary

• Symbol: Nfil3^tm1.1Kubo
• Name: nuclear factor, interleukin 3, regulated; targeted mutation 1.1, Masato Kubo
• MGI ID: MGI:5005060
• Synonyms: E4bp4^-
• Gene: Nfil3 Location: Chr13:53121245-53135109 bp, - strand Genetic Position: Chr13, 27.68 cM
• Alliance: Nfil3^tm1.1Kubo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:172134
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129 and C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of the coding region. A loxP and a FRT-flanked neo cassette were inserted downstream of the coding region. Cre-mediated recombination removed the coding region. (J:172134)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nfil3 Mutation: 31 strains or lines available

References

• Original: J:172134 Motomura Y, et al., The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells. Nat Immunol. 2011 May;12(5):450-9
• All: 15 reference(s)