Stk38^tm1Xen
Targeted Allele Detail

Summary

• Symbol: Stk38^tm1Xen
• Name: serine/threonine kinase 38; targeted mutation 1, Taconic Biosciences
• MGI ID: MGI:5770366
• Gene: Stk38 Location: Chr17:29189854-29226969 bp, - strand Genetic Position: Chr17, 15.03 cM
• Alliance: Stk38^tm1Xen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:224932
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A selection cassette replaced the exon containing the start site. (J:224932)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stk38 Mutation: 54 strains or lines available

References

• Original: J:224932 Wen M, et al., Stk38 protein kinase preferentially inhibits TLR9-activated inflammatory responses by promoting MEKK2 ubiquitination in macrophages. Nat Commun. 2015;6:7167
• All: 1 reference(s)