Zmynd12^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Zmynd12^em1(IMPC)J
• Name: zinc finger, MYND domain containing 12; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:7344362
• Gene: Zmynd12 Location: Chr4:119279881-119311096 bp, + strand Genetic Position: Chr4, 55.38 cM
• Alliance: Zmynd12^em1(IMPC)J page
• IMPC: Zmynd12 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CTAGGTGCATATGAGCTCCA and GCTGTATTGATCCTTGTCAG, which resulted in a 355 bp deletion beginning at Chromosome 4 position 119,436,957 bp and ending after 119,437,311 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000662211 (exon 3) and 183 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 84 and early truncation 4 amino acids later. (J:188991)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Zmynd12 Mutation: 9 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 1 reference(s)