Zmynd12 MGI Mouse Gene Detail - MGI:2140259 - zinc finger, MYND domain containing 12

Symbol

Zmynd12
Name

zinc finger, MYND domain containing 12

Feature Type

protein coding gene
IDs

MGI:2140259
NCBI Gene: 332934
Alliance

genome feature page
Transcription Start Sites

2 TSS

Sequence Map

Chr4:119279881-119311096 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 4, 55.38 cM
Mapping Data

1 experiment

SNPs within 2kb

873 from dbSNP Build 142
Strain Annotations

19

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2140259	protein coding gene	Chr4:119279881-119324641 (+)
129S1/SvImJ	ENSMUSG00200011820	protein coding gene	Chr4:113184845-113216053 (+)
A/J	ENSMUSG00195030554	protein coding gene	Chr4:114430818-114461985 (+)
AKR/J	ENSMUSG00220020816	protein coding gene	Chr4:113791645-113822823 (+)
BALB/cJ	ENSMUSG00180041999	protein coding gene	Chr4:112492579-112523807 (+)
C3H/HeJ	ENSMUSG00175022327	protein coding gene	Chr4:113505754-113536984 (+)
C57BL/6NJ	ENSMUSG00215015317	protein coding gene	Chr4:114618002-114649179 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0026400	protein coding gene	Chr4:109975480-110021462 (+)
CAST/EiJ	ENSTCUG00005042354	protein coding gene	Chr4:113311629-113342881 (+)
CBA/J	ENSMUSG00210051629	protein coding gene	Chr4:113112242-113143470 (+)
DBA/2J	ENSMUSG00185045151	protein coding gene	Chr4:114665803-114696973 (+)
FVB/NJ	ENSMUSG00205017780	protein coding gene	Chr4:112588325-112619467 (+)
JF1/MsJ	ENSUMUG00000014086	protein coding gene	Chr4:114570453-114601841 (+)
LP/J	ENSMUSG00230043032	protein coding gene	Chr4:118002601-118033803 (+)
NOD/ShiLtJ	ENSMUSG00190038828	protein coding gene	Chr4:112496013-112527187 (+)
NZO/HlLtJ	ENSMUSG00225015137	protein coding gene	Chr4:123549082-123580256 (+)
PWK/PhJ	ENSLUMG00010039060	protein coding gene	Chr4:111987730-112019108 (+)
SPRET/EiJ	ENSMSPG00010036020	protein coding gene	Chr4:114076542-114107300 (+)
WSB/EiJ	ENSIUOG00005037304	protein coding gene	Chr4:112805758-112836958 (+)

Human Ortholog

ZMYND12, zinc finger MYND-type containing 12

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

ZMYND12, zinc finger MYND-type containing 12
Links

HGNC:21192

NCBI Gene ID: 84217

UniProt: Q9H0C1
Chr Location

1p34.2; chr1:42430329-42456253 (-) GRCh38

MGI Vertebrate Homology

Zmynd12 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: ZMYND12
Gene Tree

Zmynd12

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Phenotype Summary

5 phenotypes from 1 allele in 1 genetic background
13 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

8
Chemically induced (other)

2
Endonuclease-mediated

1
Gene trapped

2
Radiation induced

1
Targeted

2
Genomic Mutations

4 involving Zmynd12
Incidental Mutations

APF
Find Mice (IMSR)

9 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

12
GO References

4

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

597
cDNA Data

3
Literature Summary

1

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

GEO

Expression Atlas
Other Vertebrate Links

Xenbase zmynd12

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All Sequences

37
RefSeq

4
UniProt

2
CCDS

CCDS18582.1

Ensembl

ENSMUSG00000070806 (Evidence)
NCBI Gene

332934

			Length	Strain/Species	Flank
genomic	332934	NCBI Gene Model \| MGI Sequence Detail	31216	C57BL/6J	± kb
transcript	NM_001014900	RefSeq \| MGI Sequence Detail	1505	Not Specified
polypeptide	A2BGJ5	UniProt \| EBI \| MGI Sequence Detail	363	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000031700 zinc finger MYND domain-containing protein 12

(term hierarchy)
InterPro Domains

IPR011990 Tetratricopeptide-like helical domain superfamily

IPR053248 Zinc finger MYND domain-containing protein

IPR002893 Zinc finger, MYND-type

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All nucleic 3

cDNA 3

Microarray probesets 3

Summaries

All 33

Developmental Gene Expression 1

Gene Ontology 4

Phenotypes 13
Earliest

J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
Latest

J:354331 Wang C, et al., ZMYND12 serves as an IDAd subunit that is essential for sperm motility in mice. Cell Mol Life Sci. 2024 Jul 27;81(1):317

TSS for Zmynd12:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr38735	Chr4:119280003-119280038 (+)	140 bp
Tssr38736	Chr4:119280039-119280078 (+)	178 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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