Ltb4r1^tm1Tksh
Targeted Allele Detail

Summary

• Symbol: Ltb4r1^tm1Tksh
• Name: leukotriene B4 receptor 1; targeted mutation 1, Takao Schimizu
• MGI ID: MGI:3701260
• Synonyms: BLT1^-
• Gene: Ltb4r1 Location: Chr14:56003419-56005951 bp, + strand Genetic Position: Chr14, 28.19 cM
• Alliance: Ltb4r1^tm1Tksh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:118995
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• A lacZ-neo was inserted into exon 2 of the locus. (J:118995)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Ltb4r1 Mutation: 20 strains or lines available

References

• Original: J:118995 Terawaki K, et al., Absence of leukotriene B4 receptor 1 confers resistance to airway hyperresponsiveness and Th2-type immune responses. J Immunol. 2005 Oct 1;175(7):4217-25
• All: 22 reference(s)