Xcl1^tm1.1Dnax
Targeted Allele Detail

Summary

• Symbol: Xcl1^tm1.1Dnax
• Name: chemokine (C motif) ligand 1; targeted mutation 1.1, DNAX Research Institute of Cellular and Molecular Biology
• MGI ID: MGI:5296620
• Gene: Xcl1 Location: Chr1:164759216-164763094 bp, - strand Genetic Position: Chr1, 72.26 cM
• Alliance: Xcl1^tm1.1Dnax page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:176844
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 2 and 3 were replaced by a floxed neo cassette which was subsequently excised. (J:176844)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Xcl1 Mutation: 10 strains or lines available

References

• Original: J:176844 Lei Y, et al., Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development. J Exp Med. 2011 Feb 14;208(2):383-94
• All: 2 reference(s)