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Targeted Allele Detail
Symbol: Cd207tm2.1Mal
Name: CD207 antigen; targeted mutation 1.1, Bernard Malissen
MGI ID: MGI:3581825
Synonyms: Cd207tm2Mal, Lang-EGFP, muLangerin-EGFP
Gene: Cd207  Location: Chr6:83648197-83654839 bp, - strand  Genetic Position: Chr6, 35.94 cM, cytoband D1-D2
Alliance: Cd207tm2.1Mal page
Germline Transmission:  Earliest citation of germline transmission: J:99114
Parent Cell Line:  CK35 (ES Cell)
Strain of Origin:  129S2/SvPas
Allele Type:    Targeted (Reporter)
Mutation:    Insertion
Mutation detailsThe following sequences were inserted in the 3' UTR: an IRES, the EGFP gene, a loxP site, the mouse Ace (angiotensin I converting enzyme (peptidyl-dipeptidase A) 1) promoter, the cre recombinase gene, a neomycin resistance gene cassette, and a second loxP site. Cre-mediated self-excision removed the cre+neo cassette in the male germline. (J:99114)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Cd207 Mutation:  18 strains or lines available
Original:  J:99114 Kissenpfennig A, et al., Dynamics and function of Langerhans cells in vivo: dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells. Immunity. 2005 May;22(5):643-54
All:  26 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory