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Transgene Detail
Symbol: Tg(TcrbBL17)1Lmor
Name: transgene insertion 1, Lucia Mori
MGI ID: MGI:3790483
Synonyms: Vb12, Vbeta12
Transgene: Tg(TcrbBL17)1Lmor  Location: unknown  
Alliance: Tg(TcrbBL17)1Lmor page
Strain of Origin:  SWR
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
Tg(TcrbBL17)1Lmor expresses 1 gene
Mutation detailsThis transgene is derived from T cell hybridoma line BL17 which encodes the rearrangement Vbeta12-Dbeta1.1-Jbeta1.1 and Cbeta1. The transgene construct was injected into SWR/J fertilized embryos and the mouse line used in this study is referred to as SWR-betaL Tg. This line carries 10 copies of the transgene insertion and expresses high levels of Tcrb mRNA in the spleen. (J:134774)
Inheritance:    Not Specified
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Original:  J:134774 Mori L, et al., Expression of a transgenic T cell receptor beta chain enhances collagen-induced arthritis. J Exp Med. 1992 Aug 1;176(2):381-8
All:  7 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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MGI 6.22
The Jackson Laboratory