Cd79b^m1Ghost
Spontaneous Allele Detail

Summary

• Symbol: Cd79b^m1Ghost
• Name: CD79B antigen; spontaneous mutation 1, Natalia Shulzhenko
• MGI ID: MGI:3829352
• Synonyms: Cd79b^mut
• Gene: Cd79b Location: Chr11:106202167-106205388 bp, - strand Genetic Position: Chr11, 68.89 cM
• Alliance: Cd79b^m1Ghost page

Mutation origin

• Strain of Origin: B10.Cg-Ptprc^a H2^a

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: This is a spontaneous mutation in exon 3. A G-to-A transition has occurred at coding nucleotide 224 resulting in a change at codon 75 from tryptophan to a stop codon (p.W75*). (J:157450)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd79b Mutation: 36 strains or lines available

References

• Original: J:157450 Shulzhenko N, et al., Spontaneous mutation in the Cd79b gene leads to a block in B-lymphocyte development at the C' (early pre-B) stage. Genes Immun. 2009 Dec;10(8):722-6
• All: 1 reference(s)