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Targeted Allele Detail
Symbol: Taf7tm1.2Dss
Name: TATA-box binding protein associated factor 7; targeted mutation 1.2, Dinah S Singer
MGI ID: MGI:5430373
Synonyms: TAF7f
Gene: Taf7  Location: Chr18:37773544-37777257 bp, - strand  Genetic Position: Chr18, 19.54 cM
Alliance: Taf7tm1.2Dss page
Germline Transmission:  Earliest citation of germline transmission: J:185745
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA loxP site was inserted upstream of the coding sequence. An FRT- and loxP-flanked neo cassette was inserted into the 3' UTR. Flp-mediated recombination removed the neo cassette and left the coding sequence floxed. (J:185745)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Taf7 Mutation:  19 strains or lines available
Original:  J:185745 Gegonne A, et al., The general transcription factor TAF7 is essential for embryonic development but not essential for the survival or differentiation of mature T cells. Mol Cell Biol. 2012 May;32(10):1984-97
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.13
The Jackson Laboratory