Trex1^em3Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Trex1^em3Gpt
• Name: three prime repair exonuclease 1; endonuclease-mediated mutation 3, GemPharmatech Co., Ltd
• MGI ID: MGI:7408568
• Gene: Trex1 Location: Chr9:108887000-108888791 bp, - strand Genetic Position: Chr9, 59.63 cM
• Alliance: Trex1^em3Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 2 deleted 56 bp (J:310174)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trex1 Mutation: 22 strains or lines available

References

• Original: J:310174 Zhang Q, et al., USP29 maintains the stability of cGAS and promotes cellular antiviral responses and autoimmunity. Cell Res. 2020 Oct;30(10):914-927
• All: 2 reference(s)