Eaf1tm1.1Zhow
Targeted Allele Detail
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Symbol: |
Eaf1tm1.1Zhow |
Name: |
ELL associated factor 1; targeted mutation 1.1, Zhou Wang |
MGI ID: |
MGI:6690858 |
Synonyms: |
Eaf1fl, Eaf1flox |
Gene: |
Eaf1 Location: Chr14:31217036-31231815 bp, + strand Genetic Position: Chr14, 19.14 cM, cytoband B
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Alliance: |
Eaf1tm1.1Zhow page
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Germline Transmission: |
Earliest citation of germline transmission:
J:288972
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129S6/SvEvTac
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: Using a recombineering approach, a loxP site flanked neomycin resistance gene was inserted into intron 1. An FRT site flanked neo cassette and a loxP site were inserted into intron 2. The two neo cassettes were removed through subsequent cre-mediated and flp-mediated recombination, leaving a conditional-ready allele with exon 2 floxed.
(J:288972)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Eaf1 Mutation: |
17 strains or lines available
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Original: |
J:288972 Pascal LE, et al., Conditional Deletion of Eaf1 Induces Murine Prostatic Intraepithelial Neoplasia in Mice. Neoplasia. 2019 Aug;21(8):752-764 |
All: |
1 reference(s) |
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