About   Help   FAQ
Due to maintenance, access to MGI may be intermittent starting at 10:00 AM ET Thursday, March 30.
Chemically induced Allele Detail
Symbol: Lystbg-grey
Name: lysosomal trafficking regulator; beige grey
MGI ID: MGI:3620573
Gene: Lyst  Location: Chr13:13764982-13953388 bp, + strand  Genetic Position: Chr13, 5.28 cM
Alliance: Lystbg-grey page
Morphologic investigation of Lystbg-grey/Lystbg-grey and +/+ wild-type mice.

Show the 1 phenotype image(s) involving this allele.

Strain of Origin:  C57BL/6
Allele Type:    Chemically induced (ENU)
Mutation:    Nucleotide substitutions
Mutation detailsA point mutation of the splice donor site of the intron between exon 25 and exon 26 caused skipping of exon 25 during RNA splicing without disrupting the reading frame. The resulting transcript has a 77 residue deletion. (J:106442)
Inheritance:    Recessive
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
In Structures Affected by this Mutation: 11 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lyst Mutation:  154 strains or lines available
Original:  J:106442 Runkel F, et al., Grey, a novel mutation in the murine Lyst gene, causes the beige phenotype by skipping of exon 25. Mamm Genome. 2006 Mar;17(3):203-10
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Copyright, and Privacy Statement
Send questions and comments to User Support.
last database update
MGI 6.22
The Jackson Laboratory