Ube2j1tm1.2Hpl
Targeted Allele Detail
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Symbol: |
Ube2j1tm1.2Hpl |
Name: |
ubiquitin-conjugating enzyme E2J 1; targeted mutation 1.2, Hidde Ploegh |
MGI ID: |
MGI:5707498 |
Gene: |
Ube2j1 Location: Chr4:33031416-33052363 bp, + strand Genetic Position: Chr4, 14.61 cM, cytoband A5
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Alliance: |
Ube2j1tm1.2Hpl page
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Abnormal head morphology of Ube2j1tm1.2Hpl/Ube2j1tm1.2Hpl sperm
Show the 3 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:218292
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Parent Cell Line: |
JM8A3.N1 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A loxP site was inserted upstream of exon 2 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 3 via homologous recombination. Recombinase mediated recombination removed the neo cassette and exons 2 and 3.
(J:218292)
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Generation of the Ube2j1tm1.1Hpl and Ube2j1tm1.2Hpl alleles |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ube2j1 Mutation: |
21 strains or lines available
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Original: |
J:218292 Koenig PA, et al., The E2 ubiquitin-conjugating enzyme UBE2J1 is required for spermiogenesis in mice. J Biol Chem. 2014 Dec 12;289(50):34490-502 |
All: |
1 reference(s) |
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