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Targeted Allele Detail
Symbol: Cd109tm1Mat
Name: CD109 antigen; targeted mutation 1, Masahide Takahashi
MGI ID: MGI:5443927
Gene: Cd109  Location: Chr9:78522828-78623535 bp, + strand  Genetic Position: Chr9, 43.65 cM
Alliance: Cd109tm1Mat page
Germline Transmission:  Earliest citation of germline transmission: J:188696
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S6/SvEvTac
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
Mutation detailsPart of exon 1 and all of exon 2 were replaced with lacZ and pgk-neo cassettes via homologous recombination. Western blot analysis confirmed the absence of protein expression in lysates from skin and testes of homozygous mice. (J:188696)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 9 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Cd109 Mutation:  102 strains or lines available
Original:  J:188696 Mii S, et al., Epidermal Hyperplasia and Appendage Abnormalities in Mice Lacking CD109. Am J Pathol. 2012 Oct;181(4):1180-9
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.24
The Jackson Laboratory