Cd300lf^tm1Toki
Targeted Allele Detail

Summary

• Symbol: Cd300lf^tm1Toki
• Name: CD300 molecule like family member F; targeted mutation 1, Toshio Kitamura
• MGI ID: MGI:5467158
• Synonyms: LMIR3^-
• Gene: Cd300lf Location: Chr11:115007040-115024818 bp, - strand Genetic Position: Chr11, 80.59 cM
• Alliance: Cd300lf^tm1Toki page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:190979
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A floxed PGK-neomycin selection cassettevreplaced most of intron 2 and all of exon 3. (J:190979)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd300lf Mutation: 19 strains or lines available

References

• Original: J:190979 Izawa K, et al., The receptor LMIR3 negatively regulates mast cell activation and allergic responses by binding to extracellular ceramide. Immunity. 2012 Nov 16;37(5):827-39
• All: 7 reference(s)