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Targeted Allele Detail
Symbol: Cfc1tm1Cbm
Name: cryptic, EGF-CFC family member 1; targeted mutation 1, Carmen Birchmeier
MGI ID: MGI:2181718
Synonyms: cryptic-
Gene: Cfc1  Location: Chr1:34574729-34583392 bp, + strand  Genetic Position: Chr1, 13.34 cM, cytoband B
Alliance: Cfc1tm1Cbm page
Germline Transmission:  Earliest citation of germline transmission: J:58530
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA lacZ-neo fusion to the ATG codon of the gene was introduced via homologous recombination and results in the replacement of exons 1-4. Homozygous mutant embryos were identified by Southern blot analysis. (J:58530)
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
In Mice Carrying this Mutation: 12 assay results
In Structures Affected by this Mutation: 8 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cfc1 Mutation:  22 strains or lines available
Original:  J:58530 Gaio U, et al., A role of the cryptic gene in the correct establishment of the left-right axis. Curr Biol. 1999 Nov 18;9(22):1339-42
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.13
The Jackson Laboratory