Nlrp2^tm1.2Itl
Targeted Allele Detail

Summary

• Symbol: Nlrp2^tm1.2Itl
• Name: NLR family, pyrin domain containing 2; targeted mutation 1.2, Ingenious Targeting Laboratory
• MGI ID: MGI:6343489
• Synonyms: Nlrp2^-
• Gene: Nlrp2 Location: Chr7:5301546-5354034 bp, - strand Genetic Position: Chr7, 3.07 cM, cytoband A1
• Alliance: Nlrp2^tm1.2Itl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:237496
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exon 5 is deleted following cre-mediated recombination of flanking loxP sites. (J:237496)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nlrp2 Mutation: 73 strains or lines available

References

• Original: J:237496 Kuchmiy AA, et al., NLRP2 controls age-associated maternal fertility. J Exp Med. 2016 Dec 12;213(13):2851-2860
• All: 1 reference(s)