Cx3cl1^tm1Sgs
Targeted Allele Detail

Summary

• Symbol: Cx3cl1^tm1Sgs
• Name: C-X3-C motif chemokine ligand 1; targeted mutation 1, Sulpicio G Soriano
• MGI ID: MGI:3526846
• Synonyms: CX3CL1^tm, FKN^-, NTN^-
• Gene: Cx3cl1 Location: Chr8:95498808-95509055 bp, + strand Genetic Position: Chr8, 46.79 cM
• Alliance: Cx3cl1^tm1Sgs page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:95634
• Parent Cell Line: RF8 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The majority of the coding sequence was replaced with a neomycin resistance gene. Northern blot analysis of brains from mutants confirmed the absence of transcript. (J:95634)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cx3cl1 Mutation: 32 strains or lines available

References

• Original: J:95634 Soriano SG, et al., Mice deficient in fractalkine are less susceptible to cerebral ischemia-reperfusion injury. J Neuroimmunol. 2002 Apr;125(1-2):59-65
• All: 3 reference(s)