Ms4a6d^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ms4a6d^em1Cya
• Name: membrane-spanning 4-domains, subfamily A, member 6D; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:6384846
• Synonyms: Ms4a6d^em1Cgen
• Gene: Ms4a6d Location: Chr19:11563970-11582150 bp, - strand Genetic Position: Chr19, 8.45 cM, cytoband B
• Alliance: Ms4a6d^em1Cya page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exons 2 and 3. (J:281762)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ms4a6d Mutation: 28 strains or lines available

References

• Original: J:281762 Huang X, et al., VSIG4 mediates transcriptional inhibition of Nlrp3 and Il-1beta in macrophages. Sci Adv. 2019 Jan;5(1):eaau7426
• All: 3 reference(s)