Sell^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Sell^m2Btlr
• Name: selectin, lymphocyte; mutation 2, Bruce Beutler
• MGI ID: MGI:5775035
• Synonyms: dim_sum2
• Gene: Sell Location: Chr1:163889556-163908354 bp, + strand Genetic Position: Chr1, 71.37 cM
• Alliance: Sell^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to T transversion at base pair 164,065,661 (v38) on chromosome 1, or base pair 3,849 in the GenBank genomic region NC_000067. The mutation corresponds to residue 558 in the mRNA sequence NM_011346 within exon 3 of 9 total exons and residue 558 in the mRNA sequence within exon 3 of 8 total exons. The mutation results in a substitution of Lys 149 (K149) to a premature stop codon (K149*). (J:231806)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sell Mutation: 41 strains or lines available

References

• Original: J:231806 Choi JH, et al., Mutagenetix entry for dim_sum2. MGI Direct Data Submission. 2016
• All: 1 reference(s)