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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Sellm2Btlr
mutation 2, Bruce Beutler
MGI:5775035
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Sellm2Btlr/Sellm2Btlr C57BL/6J-Sellm2Btlr MGI:5775065


Genotype
MGI:5775065
hm1
Allelic
Composition		 Sellm2Btlr/Sellm2Btlr
Genetic
Background		 C57BL/6J-Sellm2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sellm2Btlr mutation (0 available); any Sell mutation (41 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased single-positive T cell number ( J:231806 )
• naive CD4+ and CD8+ T cells
decreased response to antigen ( J:231806 )
• diminished T-dependent antibody responses to ovalbumin administered with aluminum hydroxide (OVA/Alum)

hematopoietic system
decreased single-positive T cell number ( J:231806 )
• naive CD4+ and CD8+ T cells




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory