Exph5^tm1Tiz
Targeted Allele Detail

Summary

• Symbol: Exph5^tm1Tiz
• Name: exophilin 5; targeted mutation 1, Tetsuro Izumi
• MGI ID: MGI:6802112
• Gene: Exph5 Location: Chr9:53212970-53288814 bp, + strand Genetic Position: Chr9, 29.12 cM
• Alliance: Exph5^tm1Tiz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:313415
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The targeting construct replaced exon 6 with a floxed selection cassette. (J:313415)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Exph5 Mutation: 58 strains or lines available

References

• Original: J:313415 Okunishi K, et al., Exophilin-5 regulates allergic airway inflammation by controlling IL-33-mediated Th2 responses. J Clin Invest. 2020 Jul 1;130(7):3919-3935
• All: 1 reference(s)