Irf1^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Irf1^m2Btlr
• Name: interferon regulatory factor 1; mutation 2, Bruce Beutler
• MGI ID: MGI:6269374
• Synonyms: endeka2
• Gene: Irf1 Location: Chr11:53660841-53669200 bp, + strand Genetic Position: Chr11, 32.0 cM
• Alliance: Irf1^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced C to G transversion at base pair 53,771,322 (v38) on chromosome 11, or base pair 1,294 in the GenBank genomic region NC_000077. The mutation corresponds to residue 303 in the mRNA sequence NM_008390 within exon 2 of 10 total exons. The mutation results in a leucine to valine substitution at position 12 (L12V) in the IRF1 protein. (J:267675)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Irf1 Mutation: 19 strains or lines available

References

• Original: J:267675 Zhong X, et al., Mutagenetix entry for endeka2. MGI Direct Data Submission. 2018
• All: 1 reference(s)