Nup210^tm1.1Mdan
Targeted Allele Detail

Summary

• Symbol: Nup210^tm1.1Mdan
• Name: nucleoporin 210; targeted mutation 1.1, Maximiliano A D'Angelo
• MGI ID: MGI:6830911
• Gene: Nup210 Location: Chr6:90990050-91093811 bp, - strand Genetic Position: Chr6, 40.3 cM
• Alliance: Nup210^tm1.1Mdan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:282451
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The targeting construct floxed exon 2. Cre-mediated recombination removed exon 2. (J:282451)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nup210 Mutation: 85 strains or lines available

References

• Original: J:282451 Borlido J, et al., Nuclear pore complex-mediated modulation of TCR signaling is required for naive CD4(+) T cell homeostasis. Nat Immunol. 2018 Jun;19(6):594-605
• All: 1 reference(s)