Idh3g^em1(IMPC)Bay
Endonuclease-mediated Allele Detail

Summary

• Symbol: Idh3g^em1(IMPC)Bay
• Name: isocitrate dehydrogenase 3 (NAD+), gamma; endonuclease-mediated mutation 1, Baylor College of Medicine
• MGI ID: MGI:6257659
• Gene: Idh3g Location: ChrX:72822569-72830471 bp, - strand Genetic Position: ChrX, 37.41 cM, cytoband A7.3-B
• Alliance: Idh3g^em1(IMPC)Bay page
• IMPC: Idh3g gene page

Mutation origin

• Strain of Origin: C57BL/6N
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at Baylor College of Medicine using Cas9 and guides with spacer sequences AGTGCTTAGGGGCTAGTCAG and CAAGGCTGTAAATAAGGAAC that targeted exon(s) ENSMUSE00001209224.2 ENSMUSE00001213601.2 ENSMUSE00001232597.2 ENSMUSE00001258229.2 ENSMUSE00001262110.2 ENSMUSE00001274739.2 ENSMUSE00001298830.2 ENSMUSE00001308486.2 ENSMUSE00001467297.2 ENSMUSE00001933039.1 ENSMUSE00001933041.1 ENSMUSE00001933043.1 ENSMUSE00001933047.1 ENSMUSE00001933049.1 ENSMUSE00001933071.1. This resulted in deletion(s) of 2807 bp (location: ChrX:72823180-72825986; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Idh3g Mutation: 23 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 4 reference(s)