Atg9a^tm1Aki
Targeted Allele Detail

Summary

• Symbol: Atg9a^tm1Aki
• Name: autophagy related 9A; targeted mutation 1, Shizuo Akira
• MGI ID: MGI:4417824
• Gene: Atg9a Location: Chr1:75157509-75168654 bp, - strand Genetic Position: Chr1, 38.62 cM
• Alliance: Atg9a^tm1Aki page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:155552
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: Exons 6 through 11 were replaced with a neomycin resistance cassette by homologues recombination. RT-PCR analysis indicates the presence of a truncated mRNA. (J:155552)

Generation of the Atg9a^tm1Aki allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atg9a Mutation: 43 strains or lines available

References

• Original: J:155552 Saitoh T, et al., Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response. Proc Natl Acad Sci U S A. 2009 Dec 8;106(49):20842-6
• All: 6 reference(s)