Bnip3l^tm1Ney
Targeted Allele Detail

Summary

• Symbol: Bnip3l^tm1Ney
• Name: BCL2/adenovirus E1B interacting protein 3-like; targeted mutation 1, Paul A Ney
• MGI ID: MGI:3819930
• Synonyms: Nix^-
• Gene: Bnip3l Location: Chr14:67222688-67246326 bp, - strand Genetic Position: Chr14, 34.6 cM
• Alliance: Bnip3l^tm1Ney page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:141545
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 4 and 5 were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on Friend virus-infected erythroid cell extracts. (J:141545)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bnip3l Mutation: 40 strains or lines available

References

• Original: J:141545 Schweers RL, et al., NIX is required for programmed mitochondrial clearance during reticulocyte maturation. Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19500-5
• All: 6 reference(s)