Tg(IL3,CSF2)C42Pnc
Transgene Detail

Summary

• Symbol: Tg(IL3,CSF2)C42Pnc
• Name: transgene insertion C42, Peter N Cockerill
• MGI ID: MGI:5620606
• Transgene: Tg(IL3,CSF2)C42Pnc Location: unknown
• Alliance: Tg(IL3,CSF2)C42Pnc page

Transgene origin

• Strain of Origin: CBA x C57BL/6

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(IL3,CSF2)C42Pnc expresses 2 genes
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  CSF2 (1437)

  Csf2	(MGI:1339752)

  human

  IL3 (3562)

  Il3	(MGI:96552)

• Mutation details: The transgene contains the 130 kb human genomic BAC CTD2004C12. Lines C42 (6 copies), B38 and D48 were generated. (J:219403)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:219403 Mirabella F, et al., The human IL-3/granulocyte-macrophage colony-stimulating factor locus is epigenetically silent in immature thymocytes and is progressively activated during T cell development. J Immunol. 2010 Mar 15;184(6):3043-54
• All: 4 reference(s)