Stim1^tm1Kuro
Targeted Allele Detail

Summary

• Symbol: Stim1^tm1Kuro
• Name: stromal interaction molecule 1; targeted mutation 1, Tomohiro Kurosaki
• MGI ID: MGI:5008476
• Synonyms: Stim1^f
• Gene: Stim1 Location: Chr7:101917013-102086526 bp, + strand Genetic Position: Chr7, 54.71 cM
• Alliance: Stim1^tm1Kuro page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:130477
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A floxed neomycin resistance cassette was inserted in intron 5 and a third loxP site was inserted downstream of exon 6. (J:130477)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stim1 Mutation: 46 strains or lines available

References

• Original: J:130477 Baba Y, et al., Essential function for the calcium sensor STIM1 in mast cell activation and anaphylactic responses. Nat Immunol. 2008 Jan;9(1):81-8
• All: 9 reference(s)