Tg(Vil1-cre/ERT2)23Syr
Transgene Detail
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Symbol: |
Tg(Vil1-cre/ERT2)23Syr |
Name: |
transgene insertion 23, Sylvie Robine |
MGI ID: |
MGI:3053826 |
Synonyms: |
TgvCreERT2, Tg(Vil-cre/ESR1)23Syr, vil-Cre-ERT2, vil-Cre-ERT2, villin-creERT2, villin::CreERT2, Villin-Cre(ER-T2), Villin-CreERT2 |
Transgene: |
Tg(Vil1-cre/ERT2)23Syr Location: unknown
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Alliance: |
Tg(Vil1-cre/ERT2)23Syr page
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Strain of Origin: |
(C57BL/6 x DBA/2)
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Transgene Type: |
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Transgenic (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Tg(Vil1-cre/ERT2)23Syr expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Vil1 (MGI:98930) |
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Mutation details: A 9 kb segment of the regulatory region of the mouse Vil gene drives expression of cre recombinase fused to a mutated ligand-binding domain of the human estrogen receptor. Cre recombination is inducible with tamoxifen treatment in epithelial cells all along the crypt-villus axis and in undifferentiated progenitor cells in the crypt region. This is a representative record for the two lines generated (Fo23 and Fo24) that have the same inducible expression pattern. Only 1 copy of the transgene is integrated into these lines.
(J:92295)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Vil1
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 2 strains available
Cell Lines: 0 lines available
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Original: |
J:92295 el Marjou F, et al., Tissue-specific and inducible Cre-mediated recombination in the gut epithelium. Genesis. 2004 Jul;39(3):186-93 |
All: |
391 reference(s) |
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