Zdhhc13^skc4
Chemically induced Allele Detail

Summary

• Symbol: Zdhhc13^skc4
• Name: zinc finger, DHHC domain containing 13; skin/coat 4
• MGI ID: MGI:2671845
• Synonyms: Hip14l^R425X, kojak, skc^m04Jus, skcm^04Jus
• Gene: Zdhhc13 Location: Chr7:48438751-48477188 bp, + strand Genetic Position: Chr7, 31.11 cM, cytoband B3
• Alliance: Zdhhc13^skc4 page

Small size, alopecia and kyphosis in Zdhhc13^skc4/Zdhhc13^skc4 mice

Show the 5 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Mutagenesis for Dev. Defects

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Nucleotide substitutions
• Mutation details: This phenotypic mutant was identified in an ENU mutagenesis screen at the Baylor College of Medicine. The ENU mutation resulted in a nonsense A to T mutation at c.1273 within exon 12 resulting in an R425X substitution. and a predicted truncation. Real-time PCR showed markedly reduced mRNA in mutant mice. (J:161519)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

16 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zdhhc13 Mutation: 27 strains or lines available

References

• Original: J:85113 Kile BT, et al., Functional genetic analysis of mouse chromosome 11. Nature. 2003 Sep 4;425(6953):81-6
• All: 8 reference(s)