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Tg(Ly6a-GCSAM)102AIsg
Transgene Detail
Summary
Symbol: Tg(Ly6a-GCSAM)102AIsg
Name: transgene insertion 102A, Isidro Sanchez-Garcia
MGI ID: MGI:5642051
Synonyms: Sca1-HGAL
Transgene: Tg(Ly6a-GCSAM)102AIsg  Location: unknown  
Alliance: Tg(Ly6a-GCSAM)102AIsg page
Transgene
origin
Strain of Origin:  CBA x C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Ly6a-GCSAM)102AIsg expresses 1 gene
 
Mutation detailsThe human GCSAM cDNA with a V5 tag is under the control of the mouse Ly6a (Ly-6E.1) promoter to drive expression in Sca1+ hematopoietic stem/progenitor cells and Sca1+ fraction of mature B cells. Two lines were established, 102A and 102B, with no differences in the two lines. Line 102A is entered as a representative line. (J:221238)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:221238 Romero-Camarero I, et al., Germinal centre protein HGAL promotes lymphoid hyperplasia and amyloidosis via BCR-mediated Syk activation. Nat Commun. 2013;4:1338
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory